Macrophage pathways

Resources for the Analysis of Macrophage Pathways

Pathway diagrams act as a visual representation of known interaction networks between cellular components and modelling them is fundamental to our understanding of the workings of biological systems. These pages are dedicated to bringing together the currently available resources for pathways active within macrophage. In particular, we have collated our own efforts in developing a graphical language for depicting pathways and the assembly of logic-based diagrams of signalling and effector pathways central to macrophage function. In an effort to understand the molecular networks that underpin macrophage activation we and others have been assembling a map of relevant pathways. Manual curation of the published literature has been carried out in order to define the components of these pathways and the interactions between them.

Macrophage Pathway Diagrams

These following pathway diagrams have been assembled using the modified Edinburgh Pathway Notation (mEPN) scheme. The creation of a number of large pathway diagrams has been a collaborative effort between members of The Roslin Institute, Division of Pathway Medicine, and the Centre for Systems Biology Edinburgh, University of Edinburgh.

Pathway Title	Pathway map
Integrated Macrophage Pathways v1
Integrated Macrophage Pathways v2